Center for Bioinformatics at KU

As part of our public Seminar Series
http://bioinformatics.ku.edu/seminars

May 1, Tue 2007
11:00am, MRB Conference Room

Ioan Andricioaei

University of Michigan

On the Force Dependence of Biomolecular Conformational Kinetics

Two aspects concerning the effect of external forces on biomolecular conformational kinetics will be presented. Firstly, we shall address the structural transitions, thermodynamic equlibrium and the phase diagram of DNA and RNA under torque and tension. Secondly, we shall present a stochastic path integral formalism enabling the calculation of the force dependence of the kinetic rate constant for conformational transitions.